Zhang Wenhong's Comment on mRNA Vaccine Technology Winning the Nobel Prize: Another Underlying Technology Breakthrough that Will Bring Great Changes to the Biomedical Industry
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IntroductionThe implementation of mRNA vaccine technology bypasses the nucleic acid recognition and inflammatory response formed over millions of years in humans, allowing mRNA vaccines to achieve targeted molecular expression in the body. This technology is another fundamental breakthrough in human scienceThis year's Nobel Prize in Physiology or Medicine was awarded to two "heroes" in mRNA vaccine technology, Katarin Carriko and Drew Weisman
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IntroductionThe implementation of mRNA vaccine technology bypasses the nucleic acid recognition and inflammatory response formed over millions of years in humans, allowing mRNA vaccines to achieve targeted molecular expression in the body. This technology is another fundamental breakthrough in human science
This year's Nobel Prize in Physiology or Medicine was awarded to two "heroes" in mRNA vaccine technology, Katarin Carriko and Drew Weisman. In an article published on the official account of "Huashan Infection" on October 4, Professor Zhang Wenhong, from the Infection Department of Huashan Hospital affiliated to Fudan University, commented that the landing of mRNA vaccine technology was another "steal fire" in the history of human civilization, indicating that it might bring great changes in the field of biomedicine.
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Zhang Wenhong stated that humans recognize the nucleic acid of foreign pathogens and induce a strong inflammatory response, eliminating pathogens through the inflammatory response. This is a protective mechanism formed in human evolution and the immune code for humans to survive in nature for millions of years.
The implementation of mRNA vaccine technology bypasses the nucleic acid recognition and inflammatory response formed over millions of years in humans, allowing mRNA vaccines to achieve targeted molecular expression in the body. "Zhang Wenhong wrote," This technology implementation is another fundamental technological breakthrough in human science, which will bring about unexpected changes in the field of biomedicine
Zhang Wenhong said that unlike the attenuated live vaccine, inactivated vaccine and recombinant protein vaccine in history, mRNA is a nucleic acid vaccine, which was used for the first time in the COVID-19 to fight against human diseases. It is through direct injection of mRNA to express specific proteins in the body to maintain a sustained immune response and establish strong immunity.
"Since there is no need for protein expression and purification in the vaccine manufacturing process, it is only necessary to synthesize genes. This is a great technological breakthrough in the vaccine manufacturing process, and it has obvious advantages in dealing with sudden infectious diseases such as COVID-19," commented Zhang Wenhong.
He believes that more importantly, the clinical application of such technologies has opened up a new world. The successful use of mRNA technology in vaccine development and application, as well as in response to the pandemic, signifies that humans have mastered the vaccine components or protein components required for the direct expression of nucleic acid in the body or for the treatment of other diseases. This will bring great prospects for tumor diseases, genetic diseases, and immune diseases, "said Zhang Wenhong.
Column Editor in Chief: Zhao Hanlu Text Editor: Dong Siyun Inscription Source: ICphoto Image Editor: Shao Jing
Source: Author: First Financial
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