Research has found that sedentary and metabolic syndrome patients have a higher probability of developing dementia

Tech 2023-09-18 09:17:41 Source: Network

China Daily, Washington, September 16th (Reporter Zhao Huanxin) September 17th is the "Chinese Day for the Prevention and Treatment of Alzheimer's Disease". Dementia is a serious neurological disease that concerns the global elderly population

China Daily, Washington, September 16th (Reporter Zhao Huanxin) September 17th is the "Chinese Day for the Prevention and Treatment of Alzheimer's Disease". Dementia is a serious neurological disease that concerns the global elderly population. Recent scientific research has found that adults accumulate up to 10 hours of sedentary time per day, reaching a critical point. Over 10 hours, the risk of dementia "rapidly increases". In addition, metabolic problems such as hypertension, obesity, and abnormal cholesterol can greatly increase the probability of developing dementia in later life. These research results have certain reference value for the prevention and treatment of elderly dementia in China.

Sitting still for a long time? The probability of dementia will move!

A new study has found that adults who sit for most of their day are more likely to develop dementia. The report, published on September 11, 2023 in the Journal of the American Medical Association, pointed out that people aged 60 and above who sit and watch TV or drive for more than 10 hours a day have a significantly increased risk of developing dementia. The discovery that Americans sit for an average of nearly 9.5 hours per day has caused widespread concern.

In this study, researchers had approximately 50000 adults over the age of 60 wear accelerometers and monitor their activity 24 hours a day for a week. These individuals were not diagnosed with dementia at the beginning of the study. With the help of artificial intelligence systems, scientists can distinguish between activity and sleep behavior, thereby objectively calculating the amount of time each person spends on different types of sedentary behavior. After six years of follow-up, researchers used hospital records and death registration data to determine the diagnosis of dementia and found that 414 participants had dementia. Subsequently, the scientists adjusted the research results based on factors such as age, gender, education level, race/ethnicity, chronic diseases, genetics, and personal exercise status, diet, smoking and alcohol consumption, and mental health.

The author of the study, Dr. Gene Alexander of the University of Arizona, said, "We were surprised to find that after more than 10 hours of sedentary time every day, no matter how it accumulates, the risk of developing dementia begins to rapidly increase." He added that lower levels of sedentary behavior (i.e. no more than 10 hours) do not increase the risk.

Although this study provides important clues, scientists are calling for more research to determine the causal relationship between prolonged sitting and dementia, as well as whether physical activity can reduce the risk of dementia. But the current research results are enough to alert people who sit at their desks for long periods of time: to control the total amount of sitting time every day to protect brain health.

Poor metabolic health? Increased risk of dementia

In addition to sedentary behavior, poor metabolic health is also closely related to the risk of developing dementia. Research has shown that high blood pressure, waist obesity, and abnormal cholesterol can all increase people's risk of developing dementia. This discovery not only raises concerns about cardiovascular health, but also emphasizes the importance of metabolic health for brain health.

According to a report titled "Poor metabolic health may increase the risk of dementia in later life" released by the University of Oxford on September 7th, researchers from the Oxford Population Health Center analyzed data from 176000 people at the UK's Biobank to investigate the association between metabolic syndrome and the risk of dementia in later life. These study subjects were aged 60 years or above and initially did not have dementia, but approximately 42%, or 73510 people, had metabolic syndrome. The most common five conditions were hypertension (96%), followed by high triglycerides (74%), low "good" cholesterol (i.e. LDL, low-density lipoprotein cholesterol) (72%), high waist circumference (70%), and high blood sugar (50%). Among all these research subjects, 5255 people developed dementia within 15 years.

In a report published last week in the official journal of the International Alzheimer's Association, Alzheimer's Disease and Dementia, researchers pointed out that metabolic syndrome is closely related to the risk of developing dementia. People with metabolic syndrome have a 12% higher risk of developing dementia compared to those without these diseases. More importantly, if a person has all five symptoms of metabolic syndrome mentioned above, the risk of developing dementia will increase by up to 50%.

Dr. Thomas LittleJohns, senior author and epidemiologist at the Oxford Center for Population Health, stated that increasing evidence suggests that better prevention, management, and treatment of certain health conditions can reduce the risk of developing dementia in the future.

This discovery highlights the importance of early identification and management of metabolic syndrome, which can reduce the risk of dementia in later life. The risk of dementia can be reduced through medication treatment for metabolic syndrome or lifestyle changes, including improving diet and increasing physical activity. This finding is particularly important considering the increasing number of cases of dementia worldwide and the limited effective treatment methods currently available.

Source: China Daily

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